Ontology highlight
ABSTRACT:
SUBMITTER: Chuang YC
PROVIDER: S-EPMC7274158 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Chuang Yu-Chen YC Tseng Jen-Chih JC Huang Li-Rung LR Huang Chun-Ming CM Huang Chi-Ying F CF Chuang Tsung-Hsien TH
Frontiers in immunology 20200529
Immunotherapy using checkpoint blockade has revolutionized cancer treatment, improving patient survival and quality of life. Nevertheless, the clinical outcomes of such immunotherapy are highly heterogeneous between patients. Depending on the cancer type, the patient response rates to this immunotherapy are limited to 20-30%. Based on the mechanism underlying the antitumor immune response, new therapeutic strategies have been designed with the aim of increasing the effectiveness and specificity ...[more]