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An 81 base-pair deletion in SARS-CoV-2 ORF7a identified from sentinel surveillance in Arizona (Jan-Mar 2020).


ABSTRACT: On January 26 2020, the first Coronavirus Disease 2019 (COVID-19) case was reported in Arizona of an individual with travel history (3rd case in the US). Here, we report on early SARS-CoV-2 sentinel surveillance in Tempe, Arizona. Genomic characterization identified an isolate encoding a 27 amino acid in-frame deletion in accessory protein ORF7a, the ortholog of SARS-CoV immune antagonist ORF7a/X4 .

SUBMITTER: Holland LA 

PROVIDER: S-EPMC7276018 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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An 81 base-pair deletion in SARS-CoV-2 ORF7a identified from sentinel surveillance in Arizona (Jan-Mar 2020).

Holland LaRinda A LA   Kaelin Emily A EA   Maqsood Rabia R   Estifanos Bereket B   Wu Lily I LI   Varsani Arvind A   Halden Rolf U RU   Hogue Brenda G BG   Scotch Matthew M   Lim Efrem S ES  

medRxiv : the preprint server for health sciences 20200422


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