Covid-19: the renin-angiotensin system imbalance hypothesis.
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ABSTRACT:
SUBMITTER: Lanza K
PROVIDER: S-EPMC7276636 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Publications
Covid-19: the renin-angiotensin system imbalance hypothesis.
Lanza Katharina K Perez Lucas G LG Costa Larissa B LB Cordeiro Thiago M TM Palmeira Vitria A VA Ribeiro Victor T VT Simões E Silva Ana Cristina AC
Clinical science (London, England : 1979) 20200601 11
The emergency of SARS-CoV-2 in China started a novel challenge to the scientific community. As the virus turns pandemic, scientists try to map the cellular mechanisms and pathways of SARS-CoV-2 related to the pathogenesis of Coronavirus Disease 2019 (Covid-19). After transmembrane angiotensin-converting enzyme 2 (ACE2) has been found to be SARS-CoV-2 receptor, we hypothesized an immune-hematological mechanism for Covid-19 based on renin-angiotensin system (RAS) imbalance to explain clinical, lab ...[more]
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