Ontology highlight
ABSTRACT:
SUBMITTER: Venditti M
PROVIDER: S-EPMC7277804 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Venditti Massimo M Santillo Alessandra A Falvo Sara S Fiore Maria Maddalena Di MMD Baccari Gabriella Chieffi GC Minucci Sergio S
Biomolecules 20200428 5
Cell differentiation during spermatogenesis requires a proper actin dynamic, regulated by several proteins, including formins. Disheveled-Associated-Activator of Morphogenesis1 (DAAM1) belongs to the formins and promotes actin polymerization. Our results showed that oral D-Aspartate (D-Asp) administration, an excitatory amino acid, increased DAAM1 protein levels in germ cells cytoplasm of rat testis. Interestingly, after the treatment, DAAM1 also localized in rat spermatogonia (SPG) and mouse GC ...[more]