Dataset Information

Managing anticoagulation in the COVID-19 era between lockdown and reopening phases.

ABSTRACT: Patients on anticoagulant treatment are constantly increasing, with an estimated prevalence in Italy of 2% of the total population. The recent spreadout of the COVID-19 pandemic requires a re-organization of Anticoagulation Clinics to prevent person-to-person viral diffusion and continue to offer the highest possible quality of assistance to patients. In this paper, based on the Italian Federation of Anticoagulation Clinics statements, we offer some advice aimed at improving patient care during COVID-19 pandemic, with particular regard to the lockdown and reopening periods. We give practical guidance regarding the following points: (1) re-thinking the AC organization, (2) managing patients on anticoagulants when they become infected by the virus, (3) managing anticoagulation surveillance in non-infected patients during the lockdown period, and (4) organizing the activities during the reopening phases.

SUBMITTER: Poli D

PROVIDER: S-EPMC7278243 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Managing anticoagulation in the COVID-19 era between lockdown and reopening phases.

Poli Daniela D Tosetto Alberto A Palareti Gulatiero G Barcellona Doris D Ciampa Antonio A Grandone Elvira E Manotti Cesare C Moia Marco M Squizzato Alessandro A Toschi Vincenzo V Testa Sophie S

Internal and emergency medicine 20200608 5

Patients on anticoagulant treatment are constantly increasing, with an estimated prevalence in Italy of 2% of the total population. The recent spreadout of the COVID-19 pandemic requires a re-organization of Anticoagulation Clinics to prevent person-to-person viral diffusion and continue to offer the highest possible quality of assistance to patients. In this paper, based on the Italian Federation of Anticoagulation Clinics statements, we offer some advice aimed at improving patient care during ...[more]

PMID: 32514682

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Project description:BackgroundThe COVID-19 pandemic has had a deep global impact, not only from a social and economic perspective, but also with regard to human health and the environment. To restrict transmission of the virus, the Indian government enforced a complete nationwide lockdown except for essential services and supplies in phases from 25 March to 31 May 2020. Ambient air quality in and around New Delhi, one of the most polluted cities of world, was also impacted during this period.ObjectiveThe aim of the present study was to assess and understand the impact of four different lockdown phases (LD1, LD2, LD3 and LD4) on five air pollutants (particulate matter (PM) PM2.5, PM10, nitrogen oxide (NOx), sulfur dioxide (SO2) and ozone (O3)) compared to before lockdown (BLD) at 13 air monitoring stations in and around New Delhi.MethodsSecondary data on five criteria pollutants for 13 monitoring stations in and around New Delhi for the period 1 March to 31 May 2020 was accessed from the Central Pollution Control Bard, New Delhi. Data were statistically analyzed across lockdown phases, meteorological variables, and prevailing air sources around the monitoring stations.ResultsPollutant concentrations decreased during LD1 compared to BLD except for O3 at all stations. PM2.5 and PM10 remained either close to or higher than the National Ambient Air Quality Standards (NAAQS) due to prevailing high-speed winds. During lockdown phases, NO2 decreased, whereas O3 consistently increased at all stations. This was a paradoxical situation as O3 is formed via photochemical reactions among NOx and volatile organic compounds. Principal component analysis (PCA) extracted two principal components (PC1 and PC2) which explained up to 80% of cumulative variance in data. PM2.5, PM10 and NO2 were associated with PC1, whereas PC2 had loadings of either O3 only or O3 and SO2 depending upon monitoring station.ConclusionsThe present study found that air pollutants decreased during lockdown phases, but these decreases were specific to the site(s) and pollutant(s). The decrease in pollutant concentrations during lockdown could not be attributed completely to lockdown conditions as the planetary boundary layer increased two-fold during lockdown compared to the BLD phase. Such restrictions could be applied in the future to control air pollution but should be approached with caution.Competing interestsThe authors declare no competing financial interests.

Dataset Information

Managing anticoagulation in the COVID-19 era between lockdown and reopening phases.

Publications

Managing anticoagulation in the COVID-19 era between lockdown and reopening phases.

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