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Contextualised strategies to increase childhood and adolescent vaccination coverage in South Africa: a mixed-methods study.


ABSTRACT:

Introduction

Despite the unparalleled success of immunisation in the control of vaccine preventable diseases, immunisation coverage in South Africa remains suboptimal. While many evidence-based interventions have successfully improved vaccination coverage in other countries, they are not necessarily appropriate to the immunisation needs, barriers and facilitators of South Africa. The aim of this research is to investigate barriers and facilitators to optimal vaccination uptake, and develop contextualised strategies and implementation plans to increase childhood and adolescent vaccination coverage in South Africa.

Methods

The study will employ a mixed-methods research design. It will be conducted over three iterative phases and use the Adopt, Contextualise or Adapt (ACA) model as an overarching conceptual framework. Phase 1 will identify, and develop a sampling frame of, immunisation stakeholders involved in the design, planning and implementation of childhood and human papillomavirus immunisation programmes in South Africa. Phase 2 will identify the main barriers and facilitators to, and solutions for, increasing vaccination coverage. This phase will comprise exploratory qualitative research with stakeholders and a review of existing systematic reviews on interventions for improving vaccination coverage. Using the findings from Phase 2 and the ACA model, Phase 3 will develop a set of proposed interventions and implementation action plans for improving immunisation coverage in South Africa. These plans will be discussed, revised and finalised through a series of participatory stakeholder workshops and an online questionnaire, conducted as part of Phase 3.

Ethics

Ethical approval was obtained from the South African Medical Research Council (EC018-11/2018). No risks to participants are expected. Various steps will be taken to ensure the anonymity and confidentiality of participants.

Dissemination

The study findings will be shared at stakeholder workshops, the website of Cochrane South Africa and academic publications and conferences.

SUBMITTER: Wiysonge CS 

PROVIDER: S-EPMC7279621 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Publications

Contextualised strategies to increase childhood and adolescent vaccination coverage in South Africa: a mixed-methods study.

Wiysonge Charles Shey CS   Mahasha Phetole Walter PW   Ndwandwe Duduzile Edith DE   Ngcobo Ntombenhle N   Grimmer Karen K   Dizon Janine J   Burnett Rosemary J RJ   Cooper Sara S  

BMJ open 20200604 6


<h4>Introduction</h4>Despite the unparalleled success of immunisation in the control of vaccine preventable diseases, immunisation coverage in South Africa remains suboptimal. While many evidence-based interventions have successfully improved vaccination coverage in other countries, they are not necessarily appropriate to the immunisation needs, barriers and facilitators of South Africa. The aim of this research is to investigate barriers and facilitators to optimal vaccination uptake, and devel  ...[more]

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