Ontology highlight
ABSTRACT:
SUBMITTER: Fujita R
PROVIDER: S-EPMC7280120 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Fujita Ryosuke R Hino Masato M Ebihara Takeru T Nagasato Takumi T Masuda Akitsu A Lee Jae Man JM Fujii Tsuguru T Mon Hiroaki H Kakino Kohei K Nagai Ryo R Tanaka Miyu M Tonooka Yoshino Y Moriyama Takato T Kusakabe Takahiro T
Biochemical and biophysical research communications 20200609 2
In the case of a new viral disease outbreak, an immediate development of virus detection kits and vaccines is required. For COVID-19, we established a rapid production procedure for SARS-CoV-2 spike protein (S protein) by using the baculovirus-silkworm expression system. The baculovirus vector-derived S proteins were successfully secreted to silkworm serum, whereas those formed insoluble structure in the larval fat body and the pupal cells. The ectodomain of S protein with the native sequence wa ...[more]