Ontology highlight
ABSTRACT:
SUBMITTER: Park Y
PROVIDER: S-EPMC7280265 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Park Yoonjin Y Lee Kyunghwa K Lee Chayul C Song Ahran A Kim Jinkwan J Kim Boyong B Lee SeungGwan S
Scientific reports 20200608 1
Aurea helianthus extract is associated with various properties including anti-melanogenesis, anti-oxidation, tumorigenic suppression, and immunoregulation; however, the mechanism by which it executes the immunomodulation of human vaginal epithelial cells (HVECs) remains elusive. We established three immunological functions of the extract. First, it mediated tumorigenic suppression in HVECs. Expression of cytokeratin 8, cancer antigen-125, and vimentin was dramatically downregulated in HVECs expo ...[more]