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Cefiderocol for Extensively Drug-Resistant Gram-Negative Bacterial Infections: Real-world Experience From a Case Series and Review of the Literature.


ABSTRACT: Cefiderocol is a new siderophore cephalosporin with activity against carbapenem-resistant gram-negative bacteria. Data on its clinical efficacy are limited to complicated urinary tract infections. We present a series of 3 patients successfully treated with cefiderocol for complicated health care-associated infections and review published case reports.

SUBMITTER: Zingg S 

PROVIDER: S-EPMC7284008 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Cefiderocol for Extensively Drug-Resistant Gram-Negative Bacterial Infections: Real-world Experience From a Case Series and Review of the Literature.

Zingg Sandra S   Nicoletti G Jacopo GJ   Kuster Sabine S   Junker Milena M   Widmer Andreas A   Egli Adrian A   Hinic Vladimira V   Sendi Parham P   Battegay Manuel M   Bättig Veronika V   Khanna Nina N   Tschudin-Sutter Sarah S  

Open forum infectious diseases 20200521 6


Cefiderocol is a new siderophore cephalosporin with activity against carbapenem-resistant gram-negative bacteria. Data on its clinical efficacy are limited to complicated urinary tract infections. We present a series of 3 patients successfully treated with cefiderocol for complicated health care-associated infections and review published case reports. ...[more]

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