Ontology highlight
ABSTRACT:
SUBMITTER: Yin L
PROVIDER: S-EPMC7285581 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Yin Li L Duan Jiang-Jie JJ Bian Xiu-Wu XW Yu Shi-Cang SC
Breast cancer research : BCR 20200609 1
Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor receptor 2 (HER-2), has clinical features that include high invasiveness, high metastatic potential, proneness to relapse, and poor prognosis. Because TNBC tumors lack ER, PR, and HER2 expression, they are not sensitive to endocrine therapy or HER2 treatment, and standardized TNBC treatment regimens are still lacking. ...[more]