Ontology highlight
ABSTRACT:
SUBMITTER: Micheletti G
PROVIDER: S-EPMC7288358 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Micheletti Gabriele G Boga Carla C Telese Dario D Cassani Maria Cristina MC Boanini Elisa E Nitti Patrizia P Ballarin Barbara B Ghirri Alberto A Barucca Gianni G Rinaldi Daniele D
ACS omega 20200529 22
The well-known ability to selectively drive nanomagnetic materials coated with anticancer drugs into tumor cells suggested the synthesis and the characterization of magnetic nanoparticles (MNPs) functionalized with (<i>R</i>)-9-acetoxystearic acid, the acetic ester of (<i>R</i>)-9-hydroxystearic acid (9-HSA), an antiproliferative agent active against different cancer cells. The acyl chloride of (<i>R</i>)-9-acetoxystearic acid, synthesized in two steps from 9-HSA, was reacted with (3-aminopropyl ...[more]