Dataset Information

RXR Expression in Marine Gastropods with Different Sensitivity to Imposex Development.

ABSTRACT: The superposition of male sexual characteristics in female marine gastropods (imposex) represents one of the clearest ecological examples of organotin-mediated endocrine disruption. Recent evidences suggest that signaling pathways mediated by members of the nuclear receptor superfamily, RXR and PPAR?, are involved in the development of this pseudohermaphroditic condition. Here, we identified significant differences in RXR expression in two caenogastropod species from Nuevo Gulf, Argentina, Buccinanops globulosus and Trophon geversianus, which present clear contrast in imposex incidence. In addition, B. globulosus males from a polluted and an unpolluted area showed differences in RXR expression. Conversely, PPAR? levels were similar between both analyzed species. These findings indicate specie-specific RXR and PPAR? expression, suggesting a major role of RXR in the induction of imposex.

SUBMITTER: Giulianelli S

PROVIDER: S-EPMC7289818 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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RXR Expression in Marine Gastropods with Different Sensitivity to Imposex Development.

Giulianelli Sebastián S Primost Mónica A MA Lanari Claudia C Bigatti Gregorio G

Scientific reports 20200611 1

The superposition of male sexual characteristics in female marine gastropods (imposex) represents one of the clearest ecological examples of organotin-mediated endocrine disruption. Recent evidences suggest that signaling pathways mediated by members of the nuclear receptor superfamily, RXR and PPARγ, are involved in the development of this pseudohermaphroditic condition. Here, we identified significant differences in RXR expression in two caenogastropod species from Nuevo Gulf, Argentina, Bucci ...[more]

PMID: 32528077

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Dataset Information

RXR Expression in Marine Gastropods with Different Sensitivity to Imposex Development.

Publications

RXR Expression in Marine Gastropods with Different Sensitivity to Imposex Development.

Similar Datasets

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