Ontology highlight
ABSTRACT:
SUBMITTER: Reim A
PROVIDER: S-EPMC7295792 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Reim Alexander A Ackermann Roland R Font-Mateu Jofre J Kammel Robert R Beato Miguel M Nolte Stefan S Mann Matthias M Russmann Christoph C Wierer Michael M
Nature communications 20200615 1
Transcription factors (TFs) regulate target genes by specific interactions with DNA sequences. Detecting and understanding these interactions at the molecular level is of fundamental importance in biological and clinical contexts. Crosslinking mass spectrometry is a powerful tool to assist the structure prediction of protein complexes but has been limited to the study of protein-protein and protein-RNA interactions. Here, we present a femtosecond laser-induced crosslinking mass spectrometry (fli ...[more]