Ontology highlight
ABSTRACT:
SUBMITTER: Vatlin AA
PROVIDER: S-EPMC7298395 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Data in brief 20200602
Deciphering the mechanism of action of novel anti-tuberculosis compounds is a key step in the drug development process. We have previously described a number of imidazo[1,2-<i>b</i>][1,2,4,5]tetrazines with a promising activity on <i>Mycobacterium tuberculosis</i>[1]. These compounds had predicted activity as serine‑threonine protein kinase inhibitors, however spontaneous drug resistant <i>Mycolicibacterium smegmatis mc</i> <sup><i>2</i></sup> <i>155</i> (formerly <i>Mycobacterium smegmatis</i>) ...[more]