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Deep Sequencing of Varicella-Zoster Virus in Aqueous Humor From a Patient With Acute Retinal Necrosis Presenting With Acute Glaucoma.


ABSTRACT: We report a case of acute retinal necrosis presenting with acute glaucoma preceding inflammatory signs by several days. High-throughput sequencing on aqueous humor revealed a low-level diversity in the viral genome comparable to diversity seen in cutaneous vesicles in contrast to high diversity in encephalitis.

SUBMITTER: von Hofsten J 

PROVIDER: S-EPMC7305702 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Deep Sequencing of Varicella-Zoster Virus in Aqueous Humor From a Patient With Acute Retinal Necrosis Presenting With Acute Glaucoma.

von Hofsten Joanna J   Ringlander Johan J   Norberg Peter P   Zetterberg Madeleine M   Andersson Maria M   Lindh Magnus M   Bergström Tomas T  

Open forum infectious diseases 20200526 6


We report a case of acute retinal necrosis presenting with acute glaucoma preceding inflammatory signs by several days. High-throughput sequencing on aqueous humor revealed a low-level diversity in the viral genome comparable to diversity seen in cutaneous vesicles in contrast to high diversity in encephalitis. ...[more]

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