Ontology highlight
ABSTRACT:
SUBMITTER: Gao H
PROVIDER: S-EPMC7306541 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Synthetic and systems biotechnology 20200618 2
Serine integrases have been shown to be efficient tools for metabolic pathway assembly. To further improve the flexibility and efficiency of pathway engineering via serine integrases, we explored how multiple orthogonally active serine integrases can be applied for use <i>in vitro</i> for the heterologous expression of complex biosynthesis pathways in <i>Streptomyces</i> spp., the major producers of useful bioactive natural products. The results show that multiple orthogonal serine integrases ef ...[more]