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Impact of nickel oral hyposensitization on quality of life in systemic nickel allergy syndrome.


ABSTRACT: Nickel (Ni) oral hyposensitization treatment (NiOHT) is an effective management approach for Ni allergy. No health-related quality of life (HRQoL) data exist for the pre- and post-treatment with NiOHT in systemic nickel allergy syndrome (SNAS). The aims of this study were (a) to explore HRQoL in SNAS patients, (b) to assess changes of HRQoL after 1?year of NiOHT; (c) to evaluate psychological status of patients. SNAS patients completed the Short-Form 36-Item Health Survey and Psychological General Well-Being Index before and 1?week after the end of NiOHT. Moreover, psychological state was assessed with the Minnesota Multiphasic Personality Inventory (MMPI-2). A total of 52 patients self-reported pre- and post-treatment questionnaires. HRQoL was poor at baseline. After 1?year of NiOHT, all outcome measure scores improved by about 20% with respect to baseline data (P?

SUBMITTER: Rizzi A 

PROVIDER: S-EPMC7309377 | biostudies-literature | 2020 Jan-Dec

REPOSITORIES: biostudies-literature

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Impact of nickel oral hyposensitization on quality of life in systemic nickel allergy syndrome.

Rizzi Angela A   Di Rienzo Alessia A   Buonomo Alessandro A   Aruanno Arianna A   Carusi Valentina V   Ricci Anna Giulia AG   Centrone Michele M   Mezzacappa Simona S   Romeo Lilli L   Schiavino Domenico D   Inchingolo Riccardo R   Gasbarrini Antonio A   Gasbarrini Antonio A   Nucera Eleonora E  

International journal of immunopathology and pharmacology 20200101


Nickel (Ni) oral hyposensitization treatment (NiOHT) is an effective management approach for Ni allergy. No health-related quality of life (HRQoL) data exist for the pre- and post-treatment with NiOHT in systemic nickel allergy syndrome (SNAS). The aims of this study were (a) to explore HRQoL in SNAS patients, (b) to assess changes of HRQoL after 1 year of NiOHT; (c) to evaluate psychological status of patients. SNAS patients completed the Short-Form 36-Item Health Survey and Psychological Gener  ...[more]

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