Ontology highlight
ABSTRACT:
SUBMITTER: Vanderstraeten J
PROVIDER: S-EPMC7312479 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Vanderstraeten Jessica J Baselet Bjorn B Buset Jasmine J Ben Said Naziha N de Ville de Goyet Christine C Many Marie-Christine MC Gérard Anne-Catherine AC Derradji Hanane H
International journal of molecular sciences 20200531 11
Breast cancer remains a major concern and its physiopathology is influenced by iodine deficiency (ID) and radiation exposure. Since radiation and ID can separately induce oxidative stress (OS) and microvascular responses in breast, their combination could additively increase these responses. Therefore, ID was induced in MCF7 and MCF12A breast cell lines by medium change. Cells were then X-irradiated with doses of 0.05, 0.1, or 3 Gy. In MCF12A cells, both ID and radiation (0.1 and 3 Gy) increased ...[more]