Ontology highlight
ABSTRACT:
SUBMITTER: Xu Z
PROVIDER: S-EPMC7312537 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Xu Zhipeng Z Ji Minjun M Li Chen C Du Xiaofeng X Hu Wei W McManus Donald Peter DP You Hong H
International journal of molecular sciences 20200604 11
We characterized <i>Schistosoma japonicum</i> HSP40 (Sjp40) and HSP90α (Sjp90α) in this study. Western blot analysis revealed both are present in soluble egg antigens and egg secretory proteins, implicating them in triggering the host immune response after secretion from eggs into host tissues. These observations were confirmed by immunolocalization showing both HSPs are located in the Reynolds' layer within mature eggs, suggesting they are secreted by miracidia and accumulate between the envelo ...[more]