Stage-Specific Effects of Ionizing Radiation during Early Development.
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ABSTRACT:
SUBMITTER: Honjo Y
PROVIDER: S-EPMC7312565 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Publications
Stage-Specific Effects of Ionizing Radiation during Early Development.
Honjo Yasuko Y Ichinohe Tatsuo T
International journal of molecular sciences 20200601 11
Early embryonic cells are sensitive to genotoxic stressors such as ionizing radiation. However, sensitivity to these stressors varies depending on the embryonic stage. Recently, the sensitivity and response to ionizing radiation were found to differ during the preimplantation period. The cellular and molecular mechanisms underlying the change during this period are beginning to be elucidated. In this review, we focus on the changes in radio-sensitivity and responses to ionizing radiation during ...[more]
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