Ontology highlight
ABSTRACT:
SUBMITTER: Urban BE
PROVIDER: S-EPMC7313398 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Urban Ben E BE Xiao Lei L Dong Biqin B Chen Siyu S Kozorovitskiy Yevgenia Y Zhang Hao F HF
Journal of biophotonics 20171109 3
Visualizing fine neuronal structures deep inside strongly light-scattering brain tissue remains a challenge in neuroscience. Recent nanoscopy techniques have reached the necessary resolution but often suffer from limited imaging depth, long imaging time or high light fluence requirements. Here, we present two-photon super-resolution patterned excitation reconstruction (2P-SuPER) microscopy for 3-dimensional imaging of dendritic spine dynamics at a maximum demonstrated imaging depth of 130 μm in ...[more]