Ontology highlight
ABSTRACT:
SUBMITTER: Didangelos A
PROVIDER: S-EPMC7316488 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
mSphere 20200624 3
COVID-19 is often related to hyperinflammation that drives lung or multiorgan injury. The immunopathological mechanisms that cause excessive inflammation are under investigation and constantly updated. Here, a gene network approach was used on recently published data sets to identify possible COVID-19 inflammatory mechanisms and bioactive genes. First, network analysis of putative SARS-CoV-2 cellular receptors led to the mining of a neutrophil-response signature and relevant inflammatory genes. ...[more]