Ontology highlight
ABSTRACT:
SUBMITTER: Majumder R
PROVIDER: S-EPMC7316504 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Majumder Rupamanjari R De Coster Tim T Kudryashova Nina N Verkerk Arie O AO Kazbanov Ivan V IV Ördög Balázs B Harlaar Niels N Wilders Ronald R de Vries Antoine Af AA Ypey Dirk L DL Panfilov Alexander V AV Pijnappels Daniël A DA
eLife 20200608
Homeostatic regulation protects organisms against hazardous physiological changes. However, such regulation is limited in certain organs and associated biological processes. For example, the heart fails to self-restore its normal electrical activity once disturbed, as with sustained arrhythmias. Here we present proof-of-concept of a biological self-restoring system that allows automatic detection and correction of such abnormal excitation rhythms. For the heart, its realization involves the inte ...[more]