Ontology highlight
ABSTRACT:
SUBMITTER: do Nascimento Dias J
PROVIDER: S-EPMC7316759 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
do Nascimento Dias Jhones J de Souza Silva Calliandra C de Araújo Alyne Rodrigues AR Souza Jessica Maria Teles JMT de Holanda Veloso Júnior Paulo Henrique PH Cabral Wanessa Felix WF da Glória da Silva Maria M Eaton Peter P de Souza de Almeida Leite José Roberto JR Nicola André Moraes AM Albuquerque Patrícia P Silva-Pereira Ildinete I
Scientific reports 20200625 1
Candida albicans is a major cause of human infections, ranging from relatively simple to treat skin and mucosal diseases to systemic life-threatening invasive candidiasis. Fungal infections treatment faces three major challenges: the limited number of therapeutic options, the toxicity of the available drugs, and the rise of antifungal resistance. In this study, we demonstrate the antifungal activity and mechanism of action of peptides ToAP2 and NDBP-5.7 against planktonic cells and biofilms of C ...[more]