Ontology highlight
ABSTRACT:
SUBMITTER: Salazar VA
PROVIDER: S-EPMC5061719 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Salazar Vivian A VA Arranz-Trullén Javier J Navarro Susanna S Blanco Jose A JA Sánchez Daniel D Moussaoui Mohammed M Boix Ester E
MicrobiologyOpen 20160608 5
Human antimicrobial RNases, which belong to the vertebrate RNase A superfamily and are secreted upon infection, display a wide spectrum of antipathogen activities. In this work, we examined the antifungal activity of the eosinophil RNase 3 and the skin-derived RNase 7, two proteins expressed by innate cell types that are directly involved in the host defense against fungal infection. Candida albicans has been selected as a suitable working model for testing RNase activities toward a eukaryotic p ...[more]