Ontology highlight
ABSTRACT:
SUBMITTER: Reijnen C
PROVIDER: S-EPMC7317735 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Reijnen Casper C Küsters-Vandevelde Heidi V N HVN Ligtenberg Marjolijn J L MJL Bulten Johan J Oosterwegel Marloes M Snijders Marc P L M MPLM Sweegers Sanne S de Hullu Joanne A JA Vos Maria C MC van der Wurff Anneke A M AAM van Altena Anne M AM Eijkelenboom Astrid A Pijnenborg Johanna M A JMA
International journal of cancer 20200218 2
Synchronous primary endometrial and ovarian cancers (SEOs) represent 10% of all endometrial and ovarian cancers and are assumed to develop as independent entities. We investigated the clonal relationship between endometrial and ovarian carcinomas in a large cohort classified as SEOs or metastatic disease (MD). The molecular profiles were compared to The Cancer Genome Atlas (TCGA) data to explore primary origin. Subsequently, the molecular profiles were correlated with clinical outcome. To this e ...[more]