Ontology highlight
ABSTRACT:
SUBMITTER: Fukuyama H
PROVIDER: S-EPMC7323124 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Fukuyama Hidehiro H Shinnakasu Ryo R Kurosaki Tomohiro T
Immunological reviews 20200616 1
Influenza is one of the best examples of highly mutable viruses that are able to escape immune surveillance. Indeed, in response to influenza seasonal infection or vaccination, the majority of the induced antibodies are strain-specific. Current vaccine against the seasonal strains with the strategy of surveillance-prediction-vaccine does not cover an unmet virus strain leading to pandemic. Recently, antibodies targeting conserved epitopes on the hemagglutinin (HA) protein have been identified, a ...[more]