Ontology highlight
ABSTRACT:
SUBMITTER: Huang A
PROVIDER: S-EPMC7324386 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Huang Aobo A Tang Yu Y Shi Xuetao X Jia Min M Zhu Jinheng J Yan Xiaohan X Chen Huiqin H Gu Yangnan Y
Nature communications 20200629 1
The inner nuclear membrane (INM) selectively accumulates proteins that are essential for nuclear functions; however, overaccumulation of INM proteins results in a range of rare genetic disorders. So far, little is known about how defective, mislocalized, or abnormally accumulated membrane proteins are actively removed from the INM, especially in plants and animals. Here, via analysis of a proximity-labeling proteomic profile of INM-associated proteins in Arabidopsis, we identify critical compone ...[more]