A Mini-review of the Computational Methods Used in Identifying RNA 5-Methylcytosine Sites.
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SUBMITTER: Li J
PROVIDER: S-EPMC7324889 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
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A Mini-review of the Computational Methods Used in Identifying RNA 5-Methylcytosine Sites.
Li Jianwei J Huang Yan Y Zhou Yuan Y
Current genomics 20200101 1
RNA 5-methylcytosine (m<sup>5</sup>C) is one of the pillars of post-transcriptional modification (PTCM). A growing body of evidence suggests that m<sup>5</sup>C plays a vital role in RNA metabolism. Accurate localization of RNA m<sup>5</sup>C sites in tissue cells is the premise and basis for the in-depth understanding of the functions of m<sup>5</sup>C. However, the main experimental methods of detecting m<sup>5</sup>C sites are limited to varying degrees. Establishing a computational model to ...[more]
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