Dataset Information

PRISM: A Platform for Imaging in Precision Medicine.

ABSTRACT: PURPOSE:Precision medicine requires an understanding of individual variability, which can only be acquired from large data collections such as those supported by the Cancer Imaging Archive (TCIA). We have undertaken a program to extend the types of data TCIA can support. This, in turn, will enable TCIA to play a key role in precision medicine research by collecting and disseminating high-quality, state-of-the-art, quantitative imaging data that meet the evolving needs of the cancer research community. METHODS:A modular technology platform is presented that would allow existing data resources, such as TCIA, to evolve into a comprehensive data resource that meets the needs of users engaged in translational research for imaging-based precision medicine. This Platform for Imaging in Precision Medicine (PRISM) helps streamline the deployment and improve TCIA's efficiency and sustainability. More importantly, its inherent modular architecture facilitates a piecemeal adoption by other data repositories. RESULTS:PRISM includes services for managing radiology and pathology images and features and associated clinical data. A semantic layer is being built to help users explore diverse collections and pool data sets to create specialized cohorts. PRISM includes tools for image curation and de-identification. It includes image visualization and feature exploration tools. The entire platform is distributed as a series of containerized microservices with representational state transfer interfaces. CONCLUSION:PRISM is helping modernize, scale, and sustain the technology stack that powers TCIA. Repositories can take advantage of individual PRISM services such as de-identification and quality control. PRISM is helping scale image informatics for cancer research at a time when the size, complexity, and demands to integrate image data with other precision medicine data-intensive commons are mounting.

SUBMITTER: Sharma A

PROVIDER: S-EPMC7328100 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Publications

PRISM: A Platform for Imaging in Precision Medicine.

Sharma Ashish A Tarbox Lawrence L Kurc Tahsin T Bona Jonathan J Smith Kirk K Kathiravelu Pradeeban P Bremer Erich E Saltz Joel H JH Prior Fred F

JCO clinical cancer informatics 20200601

<h4>Purpose</h4>Precision medicine requires an understanding of individual variability, which can only be acquired from large data collections such as those supported by the Cancer Imaging Archive (TCIA). We have undertaken a program to extend the types of data TCIA can support. This, in turn, will enable TCIA to play a key role in precision medicine research by collecting and disseminating high-quality, state-of-the-art, quantitative imaging data that meet the evolving needs of the cancer resea ...[more]

PMID: 32479186

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Dataset Information

PRISM: A Platform for Imaging in Precision Medicine.

Publications

PRISM: A Platform for Imaging in Precision Medicine.

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