Genetic structure of SARS-CoV-2 reflects clonal superspreading and multiple independent introduction events, North-Rhine Westphalia, Germany, February and March 2020.
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SUBMITTER: Walker A
PROVIDER: S-EPMC7336109 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
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Genetic structure of SARS-CoV-2 reflects clonal superspreading and multiple independent introduction events, North-Rhine Westphalia, Germany, February and March 2020.
Walker Andreas A Houwaart Torsten T Wienemann Tobias T Vasconcelos Malte Kohns MK Strelow Daniel D Senff Tina T Hülse Lisanna L Adams Ortwin O Andree Marcel M Hauka Sandra S Feldt Torsten T Jensen Björn-Erik BE Keitel Verena V Kindgen-Milles Detlef D Timm Jörg J Pfeffer Klaus K Dilthey Alexander T AT
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20200601 22
We whole-genome sequenced 55 SARS-CoV-2 isolates from Germany to investigate SARS-CoV-2 outbreaks in 2020 in the Heinsberg district and Düsseldorf. While the genetic structure of the Heinsberg outbreak indicates a clonal origin, reflecting superspreading dynamics from mid-February during the carnival season, distinct viral strains were circulating in Düsseldorf in March, reflecting the city's international links. Limited detection of Heinsberg strains in the Düsseldorf area despite geographical ...[more]
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