Ontology highlight
ABSTRACT:
SUBMITTER: Roozbahani GM
PROVIDER: S-EPMC7341991 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Roozbahani Golbarg Mohammadi GM Zhang Youwen Y Chen Xiaohan X Soflaee Mona Hoseini MH Guan Xiyun X
The Analyst 20191201 24
We report a label-free nanopore sensor for the detection of Zn2+ ions. By taking advantage of the cleavage of a substrate peptide by zinc-dependent enzymes, nanomolar concentrations of Zn2+ ions could be detected within minutes. Furthermore, structurally similar transition metals such as Ni2+, Co2+, Hg2+, Cu2+, and Cd2+ did not interfere with their detection. The enzymatic reaction-based nanopore sensing strategy developed in this work may find potential applications in environmental monitoring ...[more]