Ontology highlight
ABSTRACT:
SUBMITTER: Jiang J
PROVIDER: S-EPMC7346031 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Jiang Jianwen J Zheng Qiuxian Q Zhu Weiwei W Chen Xinhua X Lu Haifeng H Chen Deying D Zhang Hua H Shao Min M Zhou Lin L Zheng Shusen S
Aging 20200601 11
Metabolic reprogramming is a hallmark of tumors, including hepatocellular carcinoma (HCC). We used data from The Cancer Genome Atlas and the International Cancer Genome Consortium to assess the alterations in glycolytic and cholesterogenic genes in HCC and to determine their association with clinical features in HCC patients. Based on the gene expression profiles from these databases, we established four subtypes of HCC: cholesterogenic, glycolytic, mixed, and quiescent. The prognosis of the cho ...[more]