Ontology highlight
ABSTRACT:
SUBMITTER: Stanke-Labesque F
PROVIDER: S-EPMC7351663 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Stanke-Labesque Françoise F Gautier-Veyret Elodie E Chhun Stephanie S Guilhaumou Romain R
Pharmacology & therapeutics 20200711
Inflammation is an evolutionary process that allows survival against acute infection or injury. Inflammation is also a pathophysiological condition shared by numerous chronic diseases. In addition, inflammation modulates important drug-metabolizing enzymes and transporters (DMETs), thus contributing to intra- and interindividual variability of drug exposure. A better knowledge of the impact of inflammation on drug metabolism and its related clinical consequences would help to personalize drug tr ...[more]