Ontology highlight
ABSTRACT:
SUBMITTER: Cao ZJ
PROVIDER: S-EPMC7351785 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Cao Zhi-Jie ZJ Wei Lin L Lu Shen S Yang De-Chang DC Gao Ge G
Nature communications 20200710 1
Single-cell RNA-seq (scRNA-seq) is being used widely to resolve cellular heterogeneity. With the rapid accumulation of public scRNA-seq data, an effective and efficient cell-querying method is critical for the utilization of the existing annotations to curate newly sequenced cells. Such a querying method should be based on an accurate cell-to-cell similarity measure, and capable of handling batch effects properly. Herein, we present Cell BLAST, an accurate and robust cell-querying method built o ...[more]