Ontology highlight
ABSTRACT:
SUBMITTER: Samper Agrelo I
PROVIDER: S-EPMC7352621 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Samper Agrelo Iria I Schira-Heinen Jessica J Beyer Felix F Groh Janos J Bütermann Christine C Estrada Veronica V Poschmann Gereon G Bribian Ana A Jadasz Janusz J JJ Lopez-Mascaraque Laura L Kremer David D Martini Rudolf R Müller Hans Werner HW Hartung Hans Peter HP Adjaye James J Stühler Kai K Küry Patrick P
International journal of molecular sciences 20200618 12
Mesenchymal stem cell (MSC)-secreted factors have been shown to significantly promote oligodendrogenesis from cultured primary adult neural stem cells (aNSCs) and oligodendroglial precursor cells (OPCs). Revealing underlying mechanisms of how aNSCs can be fostered to differentiate into a specific cell lineage could provide important insights for the establishment of novel neuroregenerative treatment approaches aiming at myelin repair. However, the nature of MSC-derived differentiation and matura ...[more]