Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC7359447 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Zhang Yafang Y Crofton Elizabeth J EJ Smith Tileena E S TES Koshy Shyny S Li Dingge D Green Thomas A TA
Behavioural brain research 20190823
Novel targets for depression and anxiety disorders are necessary for the development of more effective pharmacotherapeutics. Our previous study found that the retinoic acid (RA) signaling pathway is the signaling pathway most enhanced in the nucleus accumbens (NAc) shell, a region important for depression, anxiety, and addiction. Genetic manipulations of RA signaling in the NAc affecting addiction-related behavior prompted our study of the role of retinoic acid signaling in depression-related an ...[more]