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ABSTRACT:
SUBMITTER: Sannigrahi A
PROVIDER: S-EPMC7363679 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Sannigrahi Achinta A De Nayan N Chattopadhyay Krishnananda K
Communications biology 20200715 1
It is now established that a protein can switch between multiple conformations to enable altered functions. Several pathogens including SARS COV2 utilize context-dependent conformational switches of particular proteins to invade host membrane to establish infections. In this perspective, we first discuss the understanding of the conformational switch of a protein towards the productive infections as a dark side of nature. Next, the unexplored binary combination of the sequences of SARS COV2 spik ...[more]