Ontology highlight
ABSTRACT:
SUBMITTER: Guo J
PROVIDER: S-EPMC7363852 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Guo Jiao J Jia Xiaoying X Liu Yang Y Wang Shaobo S Cao Junyuan J Zhang Bo B Xiao Gengfu G Wang Wei W
Communications biology 20200715 1
Zika virus (ZIKV) is an infectious disease that has become an important concern worldwide, it associates with neurological disorders and congenital malformations in adults, also leading to fetal intrauterine growth restriction and microcephaly during pregnancy. However, there are currently no approved vaccines or specific antiviral drugs for preventing or treating ZIKV infection. Here, we show that two FDA-approved Na<sup>+</sup>/K<sup>+</sup>-ATPase inhibitors, ouabain and digoxin, can block ZI ...[more]