Ontology highlight
ABSTRACT:
SUBMITTER: Guo T
PROVIDER: S-EPMC7364557 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Molecular neurodegeneration 20200716 1
Alzheimer's disease (AD) is the most common neurodegenerative disorder seen in age-dependent dementia. There is currently no effective treatment for AD, which may be attributed in part to lack of a clear underlying mechanism. Studies within the last few decades provide growing evidence for a central role of amyloid β (Aβ) and tau, as well as glial contributions to various molecular and cellular pathways in AD pathogenesis. Herein, we review recent progress with respect to Aβ- and tau-associated ...[more]