Ontology highlight
ABSTRACT:
SUBMITTER: Sullivan K
PROVIDER: S-EPMC7368039 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Sullivan Kylee K Zhang Yuliang Y Lopez Joseph J Lowe Mary M Noy Aleksandr A
Scientific reports 20200717 1
Carbon nanotube porins (CNTPs), short pieces of carbon nanotubes capable of self-inserting into a lipid bilayer, represent a simplified model of biological membrane channels. We have used high-speed atomic force microscopy (HS-AFM) and all-atom molecular dynamics (MD) simulations to study the behavior of CNTPs in a mixed lipid membrane consisting of DOPC lipid with a variable percentage of DMPC lipid added to it. HS-AFM data reveal that the CNTPs undergo diffusive motion in the bilayer plane. Mo ...[more]