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Silica nanoparticle supported lipid bilayers for gene delivery.

ABSTRACT: Silica nanoparticle supported cationic lipids can effectively bind plasmid DNAs and transfect mammalian cells with an efficiency that depends on both the particle size and lipid composition; here the gene delivery and expression process has been confirmed by confocal fluorescence microscopy.

SUBMITTER: Liu J 

PROVIDER: S-EPMC2867086 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature

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Silica nanoparticle supported lipid bilayers for gene delivery.

Liu Juewen J   Stace-Naughton Alison A   Brinker C Jeffrey CJ  

Chemical communications (Cambridge, England) 20090728 34

Silica nanoparticle supported cationic lipids can effectively bind plasmid DNAs and transfect mammalian cells with an efficiency that depends on both the particle size and lipid composition; here the gene delivery and expression process has been confirmed by confocal fluorescence microscopy. ...[more]

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