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Impacts of COVID-19: A research agenda to support people in their fight.

ABSTRACT: Grounded in the vast changes to work life (jobs) and home life that people are facing due to the COVID-19 pandemic (hereinafter COVID), this article presents five research directions related to COVID's impacts on jobs-i.e., job loss, job changes, job outcomes, coping, and support-and five research directions related to COVID's impact on home life-i.e., home life changes, children, life-related outcomes, social life, and support. In addition to this, I discuss overarching possible research directions and considerations for researchers, editors, and reviewers, as we continue our scientific journey to support people through this pandemic and beyond. I organize these directions and considerations into two sets of five each: focal groups that should be studied-i.e., underprivileged populations, different countries and cultural contexts, women (vs. men), workers in healthcare (frontline workers), elderly and at-risk-and five general issues and special considerations-i.e., role of technology as the oxygen, pre- vs. mid- vs. post-COVID studies, constraints on data collection/research due to COVID, evolution of COVID, and focus on contextualization (generalizability is irrelevant).

SUBMITTER: Venkatesh V

PROVIDER: S-EPMC7368151 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Impacts of COVID-19: A research agenda to support people in their fight.

Venkatesh Viswanath V

International journal of information management 20200718

Grounded in the vast changes to work life (jobs) and home life that people are facing due to the COVID-19 pandemic (hereinafter COVID), this article presents five research directions related to COVID's impacts on jobs-i.e., job loss, job changes, job outcomes, coping, and support-and five research directions related to COVID's impact on home life-i.e., home life changes, children, life-related outcomes, social life, and support. In addition to this, I discuss overarching possible research direct ...[more]

PMID: 32836648

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Project description:BackgroundWe have followed the COVID-19 clinical trial research agenda from the beginning using the COVID-evidence.org platform. Now, two years after the COVID-19 pandemic started, our aim was to re-examine this research agenda with the latest data to provide a global perspective on the research landscape with a focus on Germany.MethodsWe reviewed and updated previously published data on the COVID-19 clinical research agenda as of 28February 2022 focusing on randomized trials. We used the COVID-evidence.org platform including registry entries from ClinicalTrials.gov and the WHO International Clinical Trials Registry Platform as well as publications from the Living OVerview of Evidence platform for COVID-19 (L·OVE).ResultsTwo years on from the pandemic outbreak, there were 4,673 registered trials. The majority of these trials have remained small with a median of 120 planned participants (IQR 60-320). In the first hundred days of the pandemic most of them (50%) had been registered in China. More than two years later, the five countries with the most registered trials (alone or within a framework of international collaborations) were the USA (825 trials; 18%), Iran (619 trials; 13%), India (566 trials; 12%), China (353 trials; 8%), and Spain (309 trials; 7%). Only 119 trials were reported to have a study site in Germany (2.5% of the registered trials). Of the 4,673 trials registered, 15% (694 trials) had published their results by February 2022. The clinical research agenda has been marked by both successes, such as the large RECOVERY trial providing evidence on 10 treatments for COVID-19 including over 45,000 patients as of February 2022, and failures: worldwide only 57 randomized trials have been registered over two years that aimed to assess non-pharmaceutical interventions (e.g., face mask policies and lockdown measures) to prevent COVID-19, and only 11 of them had published results informing decisions that have an impact on the life of billions of people worldwide.ConclusionsThe COVID-19 clinical research agenda has highlighted the substantial effort of the research community but also the challenges of the clinical research ecosystem. Most importantly, it has shed light on the ability to circumvent traditional barriers and to make trials more useful even under extraordinary conditions. The time to learn our lessons and apply them is now, and the time to demonstrate how we have improved the system is before the next pandemic.

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Impacts of COVID-19: A research agenda to support people in their fight.

Publications

Impacts of COVID-19: A research agenda to support people in their fight.

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