Ontology highlight
ABSTRACT:
SUBMITTER: Apostolopoulou AA
PROVIDER: S-EPMC7368247 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Apostolopoulou Anthi A AA Lin Andrew C AC
Proceedings of the National Academy of Sciences of the United States of America 20200629 28
Neural network function requires an appropriate balance of excitation and inhibition to be maintained by homeostatic plasticity. However, little is known about homeostatic mechanisms in the intact central brain in vivo. Here, we study homeostatic plasticity in the <i>Drosophila</i> mushroom body, where Kenyon cells receive feedforward excitation from olfactory projection neurons and feedback inhibition from the anterior paired lateral neuron (APL). We show that prolonged (4-d) artificial activat ...[more]