Ontology highlight
ABSTRACT:
SUBMITTER: Zhang M
PROVIDER: S-EPMC7377869 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Zhang Manman M Zhang Lele L Li Yan Y Sun Feng F Fang Ya Y Zhang Ruijia R Wu Jin J Zhou Guanbiao G Song Huaidong H Xue Liqiong L Han Bing B Zheng Cuixia C
Aging 20200706 13
Lung cancer is the leading cause of cancer death worldwide and accounts for more than one-third of all newly diagnosed cancer cases in China. Therefore, it is of great clinical significance to explore new driver gene mutations in non-small-cell lung cancer (NSCLC). Using an initial bioinformatic analysis, we identified somatic gene mutations in 13 patients with NSCLC and confirmed these mutations by targeted sequencing in an extended validation group of 88 patients. Recurrent mutations were dete ...[more]