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High frequency response of thick REBCO coated conductors in the framework of the FCC study.

ABSTRACT: A thorough microwave response study of high temperature superconductors, considered as an alternative beam screen coating, has become integral in the design decisions for CERN's future research infrastructure. Here, we present the surface resistance [Formula: see text] of various [Formula: see text] (RE = rare earth) coated conductors available in large scale as a function of magnetic field in a broad temperature range measured by a Hakki-Coleman type resonator with resonant frequency [Formula: see text]. Analysis of the high frequency dissipation supported by DC transport characterization reveals the vortex dynamics in thick [Formula: see text] films. Determined microscopic vortex parameters span over a wide range of magnitudes and reflect the relevance of the superconducting layer's microstructure. We demonstrate that the depinning frequencies [Formula: see text] surpass [Formula: see text], which confirms the operation in high performing, low dissipation pinning regime at measurement conditions. Surface impedance extrapolation to FCC-hh conditions points towards a significant outperformance of copper by coated conductors in terms of surface resistance. The surface resistance margins would open up potential ways for a more efficient frontier circular collider.

SUBMITTER: Romanov A

PROVIDER: S-EPMC7378233 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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High frequency response of thick REBCO coated conductors in the framework of the FCC study.

Romanov Artur A Krkotić Patrick P Telles Guilherme G O'Callaghan Joan J Pont Montse M Perez Francis F Granados Xavier X Calatroni Sergio S Puig Teresa T Gutierrez Joffre J

Scientific reports 20200723 1

A thorough microwave response study of high temperature superconductors, considered as an alternative beam screen coating, has become integral in the design decisions for CERN's future research infrastructure. Here, we present the surface resistance [Formula: see text] of various [Formula: see text] (RE = rare earth) coated conductors available in large scale as a function of magnetic field in a broad temperature range measured by a Hakki-Coleman type resonator with resonant frequency [Formula: ...[more]

PMID: 32704019

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Project description:Thalamic deep brain stimulation (DBS) is an effective treatment for tremor, but the mechanisms of action remain unclear. Previous studies of human thalamic neurons to noted transient rebound bursting activity followed by prolonged inhibition after cessation of high frequency extracellular stimulation, and the present study sought to identify the mechanisms underlying this response. Recordings from 13 thalamic neurons exhibiting low threshold spike (LTS) bursting to brief periods of extracellular stimulation were made during surgeries to implant DBS leads in 6 subjects with Parkinson's disease. The response immediately after cessation of stimulation included a short epoch of burst activity, followed by a prolonged period of silence before a return to LTS bursting. A computational model of a population of thalamocortical relay neurons and presynaptic axons terminating on the neurons was used to identify cellular mechanisms of the observed responses. The model included the actions of neuromodulators through inhibition of a non-pertussis toxin sensitive K(+) current (I(KL)), activation of a pertussis toxin sensitive K(+) current (I(KG)), and a shift in the activation curve of the hyperpolarization-activated cation current (I(h)). The model replicated well the measured responses, and the prolonged inhibition was associated most strongly with changes in I(KG) while modulation of I(KL) or I(h) had minimal effects on post-stimulus inhibition suggesting that neuromodulators released in response to high frequency stimulation are responsible for mediating the post-stimulation bursting and subsequent long duration silence of thalamic neurons. The modeling also indicated that the axons of the model neurons responded robustly to suprathreshold stimulation despite the inhibitory effects on the soma. The findings suggest that during DBS the axons of thalamocortical neurons are activated while the cell bodies are inhibited thus blocking the transmission of pathological signals through the network and replacing them with high frequency regular firing.

Dataset Information

High frequency response of thick REBCO coated conductors in the framework of the FCC study.

Publications

High frequency response of thick REBCO coated conductors in the framework of the FCC study.

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