Ontology highlight
ABSTRACT:
SUBMITTER: Yano H
PROVIDER: S-EPMC7379913 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Yano Hirokazu H Alam Md Zobaidul MZ Rimbara Emiko E Shibata Tomoko F TF Fukuyo Masaki M Furuta Yoshikazu Y Nishiyama Tomoaki T Shigenobu Shuji S Hasebe Mitsuyasu M Toyoda Atsushi A Suzuki Yutaka Y Sugano Sumio S Shibayama Keigo K Kobayashi Ichizo I
Frontiers in microbiology 20200717
Epigenetic DNA base methylation plays important roles in gene expression regulation. We here describe a gene expression regulation network consisting of many DNA methyltransferases each frequently changing its target sequence-specificity. Our object <i>Helicobacter pylori</i>, a bacterium responsible for most incidence of stomach cancer, carries a large and variable repertoire of sequence-specific DNA methyltransferases. By creating a dozen of single-gene knockout strains for the methyltransfera ...[more]