Susceptibility of the Algal Toxin Microcystin-LR to UV/Chlorine Process: Comparison with Chlorination.

ABSTRACT: Microcystin-LR (MC-LR), an algal toxin (cyanotoxin) common in sources of drinking water, poses a major human health hazard due to its high toxicity. In this study, UV/chlorine was evaluated as a potentially practical and effective process for the degradation of MC-LR. Via mass spectrometry analysis, fewer chlorinated-MC-LR products were detected with UV/chlorine treatment than with chlorination, and a transformation pathway for MC-LR by UV/chlorine was proposed. Different degrees of rapid degradation of MC-LR were observed with varying pH (6-10.4), oxidant dosage (0.5-3 mg L-1), natural organic matter (0-7 mg L-1), and natural water sources. In contrast to the formation of primarily chloroform and dichloroacetic acid in deionized water where MC-LR serves as the only carbon source, additional chlorinated disinfection byproducts were produced when sand filtered natural water was used as a background matrix. The UV/chlorine treated samples also showed quantitatively less cytotoxicity in vitro in HepaRG human liver cell line tests than chlorination treated samples. Following 16 min (96 mJ cm-2) of UV irradiation combined with 1.5 mg L-1 chlorine treatment, the cell viability of the samples increased from 80% after exposure to 1 mg L-1 MC-LR to 90%, while chlorination treatment evidenced no reduction in cytotoxicity with the same reaction time.

SUBMITTER: Duan X 

PROVIDER: S-EPMC7382943 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature