Ontology highlight
ABSTRACT:
SUBMITTER: Biancotti JC
PROVIDER: S-EPMC7383650 | biostudies-literature | 2020 Jan-Dec
REPOSITORIES: biostudies-literature
Biancotti Juan C JC Walker Kendal A KA Jiang Guihua G Di Bernardo Julie J Shea Lonnie D LD Kunisaki Shaun M SM
Journal of tissue engineering 20200101
Studying how the fetal spinal cord regenerates in an <i>ex vivo</i> model of spina bifida repair may provide insights into the development of new tissue engineering treatment strategies to better optimize neurologic function in affected patients. Here, we developed hydrogel surgical patches designed for prenatal repair of myelomeningocele defects and demonstrated viability of both human and rat neural progenitor donor cells within this three-dimensional scaffold microenvironment. We then establi ...[more]