Ontology highlight
ABSTRACT:
SUBMITTER: Hu CJ
PROVIDER: S-EPMC7390729 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Hu Chin-Ju CJ Lu Ying-Chang YC Tsai Yi-Hsiu YH Cheng Haw-Yuan HY Takeda Hiroki H Huang Chun-Ying CY Xiao Ru R Hsu Chuan-Jen CJ Tsai Jin-Wu JW Vandenberghe Luk H LH Wu Chen-Chi CC Cheng Yen-Fu YF
Molecular therapy. Methods & clinical development 20200624
Sensorineural hearing loss is one of the most common sensory disorders worldwide. Recent advances in vector design have paved the way for investigations into the use of adeno-associated vectors (AAVs) for hearing disorder gene therapy. Numerous AAV serotypes have been discovered to be applicable to inner ears, constituting a key advance for gene therapy for sensorineural hearing loss, where transduction efficiency of AAV in inner ear cells is critical for success. One such viral vector, AAV2/Anc ...[more]